invivoPKfit 2.0.2
- Minor bug fix for adjusting rate constants after fitting to standard
“1/hour”.
 
- Improved 
pk object organization and CLI message
outputs.
 
- Externalized parallel processing for fitting with 
mirai
and purrr 1.1.0. Now, users should set the number of
processes through those interfaces if parallel or distributed computing
is desired.
 
- Setting data, error, NCA, sd, and LOQ groups now uses unquoted data
variable names, the latter two have their own separate
pkproto object setups: stat_sd_group() and
stat_loq_group().
 
- Parameter starts and and estimates are stored as singular values in
a 
list-column, which allows character vector constant
parameters for calls to more complex PBTK models, see
model_httk_gas_pbtk.
 
- Users may now set specific parameters to optimize and specific start
values using the new functions 
set_params_optimize() and
set_params_starts(). 
- Updated 
cvt object to align with latest CvTdb
release. 
invivoPKfit 2.0.1
- Ensured only optimized parameters will be used when calculating AIC.
This is really only a concern when using models that hold many of the
total parameters constant.
 
- Added a new feature allowing users to calculate log-likelihood from
predictions generated outside invivoPKfit.
 
- Updated documentation and cleaned up vignettes.
 
invivoPKfit 2.0.0
- Initial CRAN submission.
 
- Redesigned package to an S3 object-oriented approach with some
ggplot2-like syntax.
 
- Re-factored function/method code to ensure the code base is more
legible to future contributors.
 
- Implemented messages that save and update data processing
“status”.
 
- Parallel processing parameter optimization was added as an option to
take advantage of multi-processing cores.
 
- Included more chemical records than previously published in the
cvt object, represented a processed portion of the CvTdb
database.