grantham: Calculate the Grantham Distance

A minimal set of routines to calculate the Grantham distance <doi:10.1126/science.185.4154.862>. The Grantham distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.

Version: 0.1.4
Depends: R (≥ 4.1.0)
Imports: tibble, dplyr
Suggests: spelling, testthat (≥ 3.0.0)
Published: 2025-05-31
DOI: 10.32614/CRAN.package.grantham
Author: Ramiro Magno ORCID iD [aut, cre], Isabel Duarte ORCID iD [aut], Ana-Teresa Maia ORCID iD [aut], University of Algarve [fnd], CINTESIS [fnd], Pattern Institute ROR ID [cph, fnd]
Maintainer: Ramiro Magno <rmagno at pattern.institute>
BugReports: https://github.com/patterninstitute/grantham/issues
License: MIT + file LICENSE
URL: https://www.pattern.institute/grantham/, https://github.com/patterninstitute/grantham
NeedsCompilation: no
Language: en-US
Materials: README, NEWS
CRAN checks: grantham results

Documentation:

Reference manual: grantham.html , grantham.pdf

Downloads:

Package source: grantham_0.1.4.tar.gz
Windows binaries: r-devel: grantham_0.1.4.zip, r-release: grantham_0.1.4.zip, r-oldrel: grantham_0.1.4.zip
macOS binaries: r-release (arm64): grantham_0.1.4.tgz, r-oldrel (arm64): grantham_0.1.4.tgz, r-release (x86_64): grantham_0.1.4.tgz, r-oldrel (x86_64): grantham_0.1.4.tgz
Old sources: grantham archive

Reverse dependencies:

Reverse imports: agvgd

Linking:

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