adaptIVPT: Adaptive Bioequivalence Design for In-Vitro Permeation Tests
Contains functions carrying out adaptive procedures using mixed scaling approach to establish bioequivalence for in-vitro permeation test (IVPT) data. Currently, the package provides procedures based on parallel replicate design and balanced data, according to the U.S. Food and Drug Administration's "Draft Guidance on Acyclovir" <https://www.accessdata.fda.gov/drugsatfda_docs/psg/Acyclovir_topical%20cream_RLD%2021478_RV12-16.pdf>. Potvin et al. (2008) <doi:10.1002/pst.294> provides the basis for our adaptive design (see Method B). For a comprehensive overview of the method, refer to Lim et al. (2023) <doi:10.1002/pst.2333>. This package reflects the views of the authors and should not be construed to represent the views or policies of the U.S. Food and Drug Administration.
| Version: |
1.1.0 |
| Depends: |
R (≥ 3.4) |
| Imports: |
Rcpp, rgl |
| LinkingTo: |
Rcpp, RcppArmadillo, RcppProgress |
| Suggests: |
knitr, rmarkdown |
| Published: |
2024-01-26 |
| DOI: |
10.32614/CRAN.package.adaptIVPT |
| Author: |
Daeyoung Lim [aut, cre],
Elena Rantou [ctb],
Jessica Kim [ctb],
Sungwoo Choi [ctb],
Nam Hee Choi [ctb],
Stella Grosser [ctb] |
| Maintainer: |
Daeyoung Lim <Daeyoung.Lim at fda.hhs.gov> |
| License: |
GPL (≥ 3) |
| NeedsCompilation: |
yes |
| Citation: |
adaptIVPT citation info |
| Materials: |
NEWS |
| In views: |
ClinicalTrials |
| CRAN checks: |
adaptIVPT results |
Documentation:
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